To get a feel for the importance of substance in the continuity of life and many other issues, you could study books like: "The Possibility of Metaphysics: Substance, Identity, and Time" by E. J. Lowe; Clarendon Press, 1998.
For now, I direct my attention to the process of creation as a whole, but I'll come back to considerations of substance when necessary to my investigations. Keep in mind that I use the old Eastern method of study: first get a global picture, then descend into more detailed descriptions. Ponder about these things and your intuition will develop alongside with your experience in life.